Use a reputable brand of Nicotinamide Mononucleotide (NMN) or Nicotinamide Riboside (NR), as quality in this space varies wildly.
The Wild West of NAD+
I was so excited by the science of NAD+ precursors that I bought the first, cheapest NMN powder I could find. It did absolutely nothing. I had entered the Wild West. The market is flooded with fake, underdosed, and unstable products. I switched to a highly reputable, third-party tested brand. The difference was night and day. I felt a clean, profound, and undeniable surge in my cellular energy. With a molecule this important, you cannot afford to gamble on quality. Your cells know the difference.
Stop taking NMN/NR without also supporting methylation. Do take it with a methyl donor like TMG (trimethylglycine).
The Methylation Tax
I started taking NMN and felt an amazing boost in my energy and vitality. But after a few weeks, I started to feel a little off, a bit anxious. I had run into the “methylation tax.” The process of recycling NMN in the body uses up methyl groups. If you don’t provide extra “donors” like TMG, you can deplete them, causing other problems. I added a scoop of TMG powder to my NMN. The “off” feeling vanished, and the benefits of the NMN became even cleaner and more powerful.
Stop expecting to feel 20 again overnight. Do take NAD+ precursors for long-term cellular repair and healthy aging.
The Slow Ship
I took my first dose of NMN and expected to wake up the next day with the boundless energy of my 20-year-old self. That was a fantasy. The reality is that NAD+ precursors are not a stimulant. They are the raw material for a long-term cellular repair project. The ship of aging took decades to go off course; it takes more than a day to turn it around. The real, profound benefits—the improved resilience, the deeper vitality—are slow, cumulative, and well worth the patient investment.
The #1 secret of longevity scientists like David Sinclair is boosting your NAD+ levels with precursors like NMN or NR.
The Sinclair Secret
I was listening to a podcast with the famous Harvard longevity scientist, David Sinclair. I was waiting for him to reveal some incredibly complex, futuristic secret to anti-aging. But his secret was surprisingly simple and accessible. He explained that a primary driver of aging is the decline of a vital molecule called NAD+. And the secret to fighting this decline is to supplement with its direct precursors, like NMN. It was a stunning revelation. The cutting edge of science wasn’t a drug; it was a simple molecule to restore what time had taken away.
The biggest lie you’ve been told about aging is that it’s a one-way street of decline. You can influence the process.
The Reversible Decline
Our culture has taught us a lie of helplessness. We’re told that aging is an unstoppable, one-way slide into frailty and decline. The science of NAD+ precursors is a direct and powerful refutation of this lie. It proves that aging is a biological process that can be influenced. By restoring the levels of this critical molecule, we can actively improve our cellular function, our energy, and our healthspan. The lie is that we are just passengers. The truth is that we can grab the wheel.
I wish I knew that as you age, your NAD+ levels plummet, and that this is a key driver of the aging process itself.
The NAD+ Nosedive
I spent my thirties and forties just accepting my slow decline in energy and recovery as “normal.” I wish I had known what was happening on a cellular level. I had no idea that my NAD+ levels had likely plummeted by 50% or more since my twenties, and that this nosedive was a primary cause of my aging, not just a symptom. The knowledge that this decline was happening, and that there were tools to address it, would have completely changed how I approached my own health and aging.
I’m just going to say it: NAD+ precursors are the most exciting anti-aging supplements of the 21st century.
The Cellular Fountain of Youth
For centuries, we have searched for the fountain of youth. We were looking in the wrong place. The science of NAD+ is showing us that the fountain isn’t a magical spring; it’s a molecule inside our own cells. The ability to restore the levels of this critical coenzyme with precursors like NMN and NR is, without a doubt, the most exciting and promising leap forward in the science of healthy aging. It’s not about living forever; it’s about feeling younger for longer.
99% of people make this one mistake when taking NMN/NR: not also taking a methyl donor like TMG, which can deplete your body’s resources.
The Unpaid Tax
A person starts taking NMN. They feel great. They don’t realize they are creating a new, hidden tax on their body’s methylation system. They are making a huge mistake. Over time, this “unpaid tax” can lead to a depletion of methyl groups, which are critical for everything from DNA expression to neurotransmitter function. By not adding a simple, cheap methyl donor like TMG, they are solving one problem while potentially creating another. Paying the tax is not optional; it’s a requirement for a smart protocol.
This one habit of boosting your NAD+ levels daily will change the way your cells age and communicate forever.
The Cellular Upgrade
I wanted to do more than just fight the symptoms of aging. I wanted to upgrade my body on a fundamental level. I started the daily habit of taking a high-quality NAD+ precursor. I know that with each dose, I am not just taking a supplement; I am providing the raw material for my cells to repair their DNA, to produce energy efficiently, and to communicate with each other effectively. This one habit has been the most profound investment I have ever made in my long-term cellular health.
If you’re still aging without supporting your fundamental NAD+ levels, you’re losing the fight against cellular decline.
The Energy Crisis of Aging
Aging, at its core, is an energy crisis. Your cells are losing their ability to produce the NAD+ they need to function. You are losing the fight, cell by cell, day by day. By not using a powerful, science-backed tool like an NAD+ precursor to refuel your cells, you are willingly letting that crisis continue. You are losing your vitality, your resilience, and your healthspan to a problem that now has a tangible, effective solution. You are choosing to let the batteries run down.